Neuroprotective effect of Capparis ovata Desf. var. palaestina Zoh. on H2O2‐induced neurotoxicity in SH‐SY5Y cells
نویسندگان
چکیده
The neuroprotective effect of flower and fruit parts Capparis ovataDesf. var. palaestinaZoh. plant was investigated in H2O2-induced cytotoxicity SH-SY5Y cells. cells were treated with H2O2alone or pretreated (COMFL) extract (COMFR) C. ovatavar. palaestina. MTT, xCELLigence, qualitative quantitative determination phytochemical constituents the extracts by LC-MS/MS methods employed. COMFL COMFR had a this stronger when presence oxidative stress. mass spectrums revealed flavonoids phenolic acid derivatives extracts. According to analyses, main compounds myristoleic acid, apigenin, caffeic acid-3-glucoside, 5-cynapoil quinic both rutin found COMFL. could inhibit H2O2induced neuronal cell death whichmight be beneficial for pretreatment stress neurodegenerative diseases
منابع مشابه
Effects of cold stratification on germination rate and percentage of caper (Capparis ovata Desf.) seeds.
Caper is an important plant because of its high adaptability to marginal agriculture fields that are not suitable for agricultural crops. Different parts of caper such as roots, fruits, flowers and buds can be used to increase the inhabitant's income. The goal of this research is to determine germination rate and percentage of caper according to different duration of cold stratification (10, 20...
متن کاملNeuroprotective effect of NPY on kainate neurotoxicity in the hippocampus.
Previous studies showed that neuropeptide Y (NPY) inhibited hippocampal epileptiform activity and that endogenous NPY might have neuroprotective effects. Therefore, in the present study, the effect of NPY microinjected intrahippocampally on the kainate-induced lesion and changes in NPY immunoreactivity (-IR) were investigated in rat hippocampus. Male Wistar rats, chronically cannulated, were un...
متن کاملthe washback effect of discretepoint vs. integrative tests on the retention of content in knowledge tests
در این پایان نامه تاثیر دو نوع تست جزیی نگر و کلی نگر بر به یادسپاری محتوا ارزیابی شده که نتایج نشان دهندهکارایی تستهای کلی نگر بیشتر از سایر آزمونها است
15 صفحه اولNeuroprotective effect of thymoquinone in acrylamide-induced neurotoxicity in Wistar rats
Objective(s):Acrylamide (ACR) has broad applications in different industries. It also forms in food during heating process. Oxidative stress has a critical role in ACR-induced neurotoxicity in both in vitro and in vivo models; therefore, the aim of the current study was the evaluation of effects of thymoquinone, the main constituent of volatile oil from Nigella sativa seeds in ACR-induced neuro...
متن کاملthe effect of e-64 on the developmental competence of sheep cocs during in vitro maturation
in the present study, the effect of e-64 at different concentrations (0.5, 1, 5 and 10 µm) added to (1) the ivm medium on oocyte nuclear maturation and developmental competence of ovine oocytes, and (2) to the ivc medium on embryonic development of ovine embryos were investigated.
ذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants
سال: 2023
ISSN: ['0717-7917']
DOI: https://doi.org/10.37360/blacpma.23.22.4.32